Research
About Our Research
The Plant Resilience Institute (PRI) at Michigan State University (MSU) is a globally renowned research center for plant resilience. We perform groundbreaking laboratory and field research addressing the challenges that climate change poses to food production and crop resilience.

PRI focuses on collaborative science across labs, disciplines, and academic departments. Figure credit: Tanya Bakija, MSU Office of Research & Innovation
As a Center of Excellence, we connect leading plant researchers and eminent interdisciplinary labs to drive unique solutions to questions in plant research. PRI is where future leaders of plant research are trained. These leaders will advance, advocate for, and prioritize the importance of plant resiliency in our society and the environment.
By focusing on convergent science, we provide the resources and the platform for groundbreaking collaborations. PRI faculty come from colleges, departments, programs, and institutions across MSU, including:
- College of Agriculture and Natural Resources
- College of Natural Science
- Department of Biochemistry and Molecular Biology (BMB)
- Department of Entomology (ENT)
- Department of Microbiology, Genetics, & Immunology (MGI)
- Department of Plant Biology (PLB)
- Department of Plant, Soil and Microbial Sciences (PSM)
- MSU-DOE Plant Research Laboratory (PRL)
- W.K. Kellogg Biological Station (KBS)
Research Initiatives
Through its innovative, bold, and transformative research, PRI is rapidly establishing itself as a hub for the global plant science research community. PRI is home to several global research initiatives, including:
C-SPIRIT
The Center for Sustainable Plant Innovation and Resilience through International Teamwork,
or C-SPIRIT, is a Global Center supported by the NSF and its partner agencies with the mission
to discover bioactive compounds that enhance plant and soil health while engaging
industry partners and stakeholders to co-develop technology, promote sustainability,
and build public trust. C-SPIRIT establishes a collaborative framework across five
countries–U.S., U.K., Canada, Japan, Republic of Korea–to pool resources, expertise,
and technologies for solving agricultural challenges.
Plant Cell Atlas
Plant Cell Atlas (PCA) is an NSF-funded grant to create a community resource that maps cellular and subcellular plant protein localization patterns, track the dynamic interactions between proteins, identify the molecular components of cellular substructures, discern complete states and transitions of specialized cell types, and integrate these disparate data points in order to generate testable models of cellular function. The PCA initiative includes plant science leaders from imaging, proteomics, genomics, nanotechnology, and data science from across the nation.
Plant Metabolic Network
The Plant Metabolic Network (PMN) is an NSF and DOE grant that aims to bring together biochemical pathway databases and research communities focused on plant metabolism. At the center of the PMN is PlantCyc, a public reference database containing pathways and their catalytic enzymes, compounds, and genes from many plant species.
Water and Life Interface Institute
WALII, or the Water and Life Interface Institute, is an NSF grant that operates as a virtual research institute bringing together labs across the U.S. to study how life continues without water from the molecular level up to evolutionary levels. WALII members seek to understand the methods used to survive desiccation and rehydration and whether or not these strategies are similar for all organisms.